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APL 4098

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Drug Profile

APL 4098

Alternative Names: APL-4098

Latest Information Update: 17 Feb 2026

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At a glance

  • Originator Apollo Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action EIF2AK4 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Acute myeloid leukaemia; Myelodysplastic syndromes

Most Recent Events

  • 06 Dec 2025 Safety, pharmacokinetics, efficacy data from phase I/II trial in Acute myeloid leukemia and Myelodysplastic syndromes presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-2025)
  • 06 Dec 2025 Apollo Therapeutics plans a clinical trials (Combination therapy) in Acute myeloid leukemia and Myelodysplastic syndromes
  • 06 Dec 2025 Pharmacodynamics data from a preclinical trial in Acute myeloid leukaemia presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2025)

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