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PI3K alpha inhibitor - OnKure Therapeutics

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Drug Profile

PI3K alpha inhibitor - OnKure Therapeutics

Alternative Names: Phosphatidylinositol 3-kinase alphaE542K, E545K inhibitor - OnKure Therapeutics; PI3KαE542K, E545K inhibitor - OnKure Therapeutics

Latest Information Update: 24 Mar 2025

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At a glance

  • Originator OnKure Therapeutics
  • Class Antineoplastics
  • Mechanism of Action Phosphatidylinositol 3 kinase alpha inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Research Breast cancer; Solid tumours

Most Recent Events

  • 10 Mar 2025 Early research in Breast cancer in USA (unspecified route) before March 2025 (OnKure Therapeutics pipeline, March 2025)
  • 26 Apr 2024 Early research in Solid tumours in USA (unspecified route) prior to April 2024 (OnKure Therapeutics pipeline, April 2024)

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