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Lutetium-177 EVS 459

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Drug Profile

Lutetium-177 EVS 459

Alternative Names: [177Lu]Lu-EVS-459; EVS-459

Latest Information Update: 03 Oct 2024

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At a glance

  • Originator Novartis Pharmaceuticals
  • Class Antineoplastics; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Non-small cell lung cancer; Ovarian cancer

Most Recent Events

  • 08 Sep 2024 Phase-I clinical trials in Non-small cell lung cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater, Inoperable/Unresectable) in USA (IV) (NCT06376253)
  • 08 Sep 2024 Phase-I clinical trials in Ovarian cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater, Inoperable/Unresectable) in USA (IV) (NCT06376253)
  • 19 Apr 2024 Novartis Pharmaceuticals plans phase I trial in Ovarian cancer and Lung cancer (Late-stage disease, Second-line therapy and greater, Metastatic disease and Inoperable/Unrespectable) in September 2024 (Parenteral) (NCT06376253)

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