Research programme: cyclin E1-directed degraders - Monte Rosa Therapeutics
Latest Information Update: 08 Apr 2025
At a glance
- Originator Monte Rosa Therapeutics
- Class Antineoplastics; Small molecules
- Mechanism of Action CCNE1 protein degraders
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Preclinical Solid tumours
Most Recent Events
- 20 Mar 2025 Monte Rosa Therapeutics announces its intention to submit an IND application for a cyclin E1 (CCNE1)-directed molecular glue degraders (MGD) in 2026
- 10 Jan 2025 Preclinical trials in Solid tumours in USA (unspecified route) before January 2025
- 09 May 2024 Early research in Solid tumours in USA (unspecified route)