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ERAS 4001

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Drug Profile

ERAS 4001

Alternative Names: ERAS-4001

Latest Information Update: 02 Mar 2026

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At a glance

  • Originator Medshine Discovery
  • Developer Erasca
  • Class 2 ring heterocyclic compounds; Antineoplastics; Pyrans; Pyrimidines; Small molecules
  • Mechanism of Action KRAS protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 02 Mar 2026 Chemical structure information (IUPAC name, Mol formula, CAS number) added
  • 24 Feb 2026 Erasca has patent protection for ERAS4001 and related compositions in USA
  • 06 Aug 2025 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Combination therapy) in USA (PO) (NCT07021898)

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