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SKB 518

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Drug Profile

SKB 518

Alternative Names: SKB-518

Latest Information Update: 10 Mar 2026

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At a glance

  • Originator Sichuan Kelun Pharmaceutical Research Institute
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA polymerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Lung cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 04 Mar 2026 Sichuan Kelun Pharmaceutical Research Institute plans a phase-II trial for Ovarian cancer, Cervical cancer and Endometrial cancer (Monotherapy, Combination Therapy, Late-stage disease, Second-line therapy or greater) in China (Parenteral, Injection), (NCT07448922)
  • 08 Sep 2025 Phase-I/II clinical trials in Solid tumours (Late-stage disease, Metastatic disease) in China (IV) (Sichuan Kelun Pharmaceutical Research Institute pipeline; September 2025)
  • 29 Aug 2025 Phase-II clinical trials in Lung cancer in China (IV) (NCT07019675)

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