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BGB B 2033

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Drug Profile

BGB B 2033

Alternative Names: BGB-B2033

Latest Information Update: 14 Jun 2025

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At a glance

  • Originator BeiGene
  • Developer BeOne Medicines
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action CD137 antigen modulators; GPC3 protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 25 Apr 2025 Pharmacodynamics data from a preclinical study in Solid tumours presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 23 Jul 2024 Phase-I clinical trials in Solid tumours (Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease) in New Zealand, China and USA (IV) (NCT06427941)
  • 23 Jul 2024 Phase-I clinical trials in Solid tumours (Monotherapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease) in New Zealand, China, and USA (IV) (NCT06427941)

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