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BGB B 2033

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Drug Profile

BGB B 2033

Alternative Names: BGB-B2033

Latest Information Update: 09 Mar 2026

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At a glance

  • Originator BeiGene
  • Developer BeOne Medicines
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action CD137 antigen agonists; GPC3 protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 26 Feb 2026 BeOne Medicines plans a phase II trial for Gastrointestinal cancer in 2H of 2026
  • 18 Dec 2025 BGB B2033 receives Fast track status from the US FDA for Liver cancer (Second-line therapy or greater)
  • 29 Oct 2025 InSysBio and BeOne Medicines agreed to collaborate on the development of BGB B 2033 for dose optimization in Solid tumour .

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