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BGB C354

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Drug Profile

BGB C354

Alternative Names: BG-C354; BGB-C354

Latest Information Update: 17 Mar 2026

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At a glance

  • Originator BeiGene
  • Developer BeOne Medicines
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 17 Mar 2026 Discontinued - Phase-I for Solid tumours (Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease) in USA, Australia, China (IV)
  • 17 Mar 2026 Discontinued - Phase-I for Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Monotherapy) in USA, Australia, China (IV)
  • 25 Apr 2025 Pharmacodynamics data from a pre-clinical trial in Solid tumours presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)

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