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PLT 012

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Drug Profile

PLT 012

Alternative Names: EI-012; PLT-012

Latest Information Update: 18 Dec 2025

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At a glance

  • Originator Elixiron Immunotherapeutics
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD36 antigen antagonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Liver cancer; Cholangiocarcinoma
  • New Molecular Entity No

Highest Development Phases

  • Preclinical Immunological disorders; Liver cancer; Liver metastases; Solid tumours

Most Recent Events

  • 15 Dec 2025 US FDA approves IND application for PLT 012 in Solid tumours
  • 15 Dec 2025 Pilatus Biosciences plans a phase I first in human trial for Solid tumours in first quarter of 2026
  • 30 Oct 2025 Pilatus Biosciences plans a phase I first-in-human trial for Liver cancer (Combination therapy) in the USA (Parenteral) in Q1 2026

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