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RGT 61159

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Drug Profile

RGT 61159

Alternative Names: RGT-61159

Latest Information Update: 02 Jun 2026

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At a glance

  • Originator Rgenta Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Proto-oncogene protein c-myb expression inhibitors; RNA splicing modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Adenoid cystic carcinoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Adenoid cystic carcinoma; Colorectal cancer
  • Preclinical Acute myeloid leukaemia

Most Recent Events

  • 22 May 2026 Efficacy and adverse events data from a phase Ia/b trial in Adenoid cystic carcinoma (ACC) or Colorectal cancer (CRC) released by Rgenta Therapeutics
  • 19 Sep 2025 RGT 61159 receives Orphan Drug status for Adenoid cystic carcinoma in USA
  • 12 Jun 2025 Pharmacodynamics data from preclinical trial in Acute myeloid leukemia presented at the 30th Congress of the European Haematology Association (EHA-2025)

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