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JSKN 021

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Drug Profile

JSKN 021

Alternative Names: JSKN-021

Latest Information Update: 25 Jun 2026

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At a glance

  • Originator Alphamab Oncology
  • Class Antineoplastics; Auristatins; Bispecific antibodies; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 25 Jun 2026 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease) in China (IV) (NCT07617727) (Alphamab Oncology pipeline, June 2026)
  • 31 May 2026 Jiangsu Alphamab Biopharmaceuticals plans a phase I trial in Solid tumours (Late-stage disease) (IV) (NCT07617727)
  • 25 Apr 2025 Pharmacodynamics data from preclinical studies in Cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)

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