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JSKN 022

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Drug Profile

JSKN 022

Alternative Names: JSKN-022

Latest Information Update: 25 Nov 2025

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At a glance

  • Originator Alphamab Oncology
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors; Programmed cell death-1 ligand-1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 24 Oct 2025 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease) in China (IV) (ChiCTR2500110741) (NCT07292402)
  • 25 Apr 2025 Pharmacodynamics data from the preclinical studies in Cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 10 Jun 2024 Alphamab Oncology has patent protection for the glycan-specific conjugation technology (Alphamab Oncology website, June 2024)

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