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DSB 2455

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Drug Profile

DSB 2455

Alternative Names: DSB-2455

Latest Information Update: 26 Jul 2024

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At a glance

  • Originator Duke Street Bio
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Poly(ADP-ribose) polymerase-1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 14 Jun 2024 Duke Street Bio plans a phase I trial for Solid tumours (Monotherapy, Combination-therapy, Late-stage disease, Second-line therapy or grater, Metastatic disease) (PO), in September 2024 (NCT06458712)
  • 01 Dec 2023 Preclinical trials in Solid tumours in United Kingdom (PO), prior to December 2023
  • 01 Dec 2023 Pharmacokinetics and pharmacodynamics data from preclinical trial in Solid tumours released by Duke Street Bio

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