Drug Profile

KH 658

Alternative Names: KH-658

Latest Information Update: 13 May 2025

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At a glance

Originator Chengdu Kanghong Pharmaceutical
Class Eye disorder therapies; Gene therapies
Mechanism of Action Gene transference; Vascular endothelial growth factor A expression inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

02 May 2025 Phase-I clinical trials in Age-related macular degeneration in USA (Intraocular) (NCT06825858)
13 Feb 2025 Chengdu Origen Biotechnology plans a phase I trial for Wet age-related macular degeneration (Treatment-experienced) in 2025 (Intraocular) (NCT06825858)
28 Jun 2024 Phase-I/II clinical trials in Age-related macular degeneration (Treatment-experienced) in China (Intraocular) (NCT06458595)

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