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CLDN18.2 targeting co-stimulatory trispecific T cell engager - Zymeworks

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Drug Profile

CLDN18.2 targeting co-stimulatory trispecific T cell engager - Zymeworks

Alternative Names: TriTCE co-stim antibody

Latest Information Update: 03 Jul 2024

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At a glance

  • Originator Zymeworks
  • Class Antineoplastics; Immunotherapies; Recombinant fusion proteins; Trispecific antibodies
  • Mechanism of Action CD28 antigen stimulants; CD3 antigen stimulants; Cytotoxic T lymphocyte stimulants; Immunologic cytotoxicity
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 05 Apr 2024 Preclinical trials in Solid tumours in Canada (Parenteral) prior to April 2024
  • 05 Apr 2024 Pharmacodynamics data from the preclinical trial in Solid tumours presented at the 115th Annual Meeting of the American Association for Cancer Research 2024 (AACR-2024)

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