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S 253272

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Drug Profile

S 253272

Alternative Names: CB-002 - Day One Biopharmaceuticals; DAY-301; MTX-13; S-253272

Latest Information Update: 04 May 2026

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At a glance

  • Originator MabCare Therapeutics
  • Developer Day One Biopharmaceuticals; MabCare Therapeutics
  • Class Alkaloids; Antineoplastics; Camptothecins; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 23 Apr 2026 Day One Biopharmaceuticals has been acquired by Servier
  • 31 Jan 2026 Day One Biopharmaceuticals has patent families directed to an ADC linker used in DAY301 and pending applications in the US before January 2026
  • 31 Jan 2026 Day One Biopharmaceuticals has patents covering compositions of matter, methods of use, and synthetic intermediates of DAY 301 in the US and pending applications in the Australia, Brazil, Canada, China, Europe, Hong Kong, India, Israel, Japan, Korea, Mexico, Singapore, South Africa, and Taiwan before January 2026

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