Drug Profile

ORN 252

Alternative Names: Anti-CD19 CAR therapy - Orna Therapeutics; ORN-252

Latest Information Update: 10 Dec 2025

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At a glance

Originator Orna Therapeutics
Class Circular RNA; Gene therapies; Immunotherapies
Mechanism of Action T lymphocyte replacements

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

Highest Development Phases

Preclinical Autoimmune disorders

Most Recent Events

07 Dec 2025 Pharmacodynamics data from a preclinical study in Autoimmune disorders released by Orna Therapeutics
03 Nov 2025 Orna Therapeutics plans to file clinical trial application in the fourth quarter of 2025
15 May 2025 Pharmacodynamics data from a preclinical study in Autoimmune disorders released by Orna Therapeutics

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