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Islatravir/Lenacapavir - Merck Sharp & Dohme/Gilead Sciences

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Drug Profile

Islatravir/Lenacapavir - Merck Sharp & Dohme/Gilead Sciences

Alternative Names: Lenacapavir/Islatravir - Merck Sharp & Dohme; MK-8591D

Latest Information Update: 05 Aug 2024

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At a glance

  • Originator Gilead Sciences; Merck Sharp & Dohme
  • Developer Gilead Sciences
  • Class Acetamides; Alkynes; Antiretrovirals; Chlorobenzenes; Fluorinated hydrocarbons; Purine nucleosides; Pyrazoles; Pyridines; Small molecules; Sulfonamides; Sulfones
  • Mechanism of Action Capsid protein inhibitors; Nucleoside reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II HIV-1 infections

Most Recent Events

  • 03 Mar 2024 Efficacy and adverse events data from a phase II trial in HIV-1 infections released by Gilead Sciences at the 31st Conference on Retroviruses and Opportunistic Infections 2024 (CROI-2024)

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