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PF614 MPAR

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Drug Profile

PF614 MPAR

Alternative Names: PF614 MPAR™; PF614-Opioid Abuse Deterrent and Overdose Protection Program

Latest Information Update: 28 Jul 2026

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At a glance

  • Originator Ensysce Biosciences
  • Class Alkaloids; Morphine derivatives; Opioid analgesics
  • Mechanism of Action Opioid delta receptor agonists; Opioid kappa receptor agonists; Opioid mu receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • No development reported Pain

Most Recent Events

  • 28 Jul 2026 No recent reports of development identified for phase-I development in Pain(In volunteers) in USA (PO)
  • 24 Nov 2024 Ensysce Biosciences initiates a phase I trial for Pain (In volunteers) in USA (PO, capsule) (NCT06500793)
  • 13 May 2024 Ensysce Biosciences received additional productive guidance from the FDA to aid the execution of our PF614 MPAR programs

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