Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

ORX 142

Next Previous
Drug Profile

ORX 142

Alternative Names: ORX-142

Latest Information Update: 20 Jun 2025

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Centessa Pharmaceuticals
  • Class Sleep disorder therapies; Small molecules
  • Mechanism of Action Orexin receptor type 2 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Hypersomnia

Most Recent Events

  • 17 Jun 2025 US FDA approves IND application for ORX 142 in Hypersomnia
  • 16 Jun 2025 Centessa Pharmaceuticals plans a phase I trial for Hypersomnia (In volunteers) in 2025
  • 26 Sep 2024 Pharmacodynamics data from preclinical trial in Hypersomnia released by Centessa Pharmaceuticals

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top