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PF 07826390

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Drug Profile

PF 07826390

Alternative Names: PF-07826390

Latest Information Update: 25 Nov 2025

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At a glance

  • Originator Pfizer
  • Class Antineoplastics; Immunoglobulins; Immunotherapies
  • Mechanism of Action Leukocyte immunoglobulin-like receptor B1 modulators; LILRB2 protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 03 Oct 2025 Pfizer terminates phase I trial in Solid tumours (Monotherapy, Combination therapy, Inoperable/Unresectable, Metastatic disease, Late-stage disease, Second-line therapy or greater) in USA (IV) (NCT06546553)
  • 05 Aug 2025 Discontinued - Phase-I for Solid tumours (Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV)
  • 05 Aug 2025 Discontinued - Phase-I for Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Monotherapy, Second-line therapy or greater) in USA (IV)

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