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APG 333

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Drug Profile

APG 333

Alternative Names: APG-333; PR-018

Latest Information Update: 19 Nov 2025

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At a glance

  • Originator Apogee Therapeutics
  • Class Antiasthmatics; Monoclonal antibodies
  • Mechanism of Action Thymic stromal lymphopoietin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Asthma

Most Recent Events

  • 10 Nov 2025 Pharmacodynamics, pharmacokinetics and adverse events data from phase-I trial in Asthma (In volunteers) released by Apogee Therapeutics
  • 17 May 2025 Pharmacodynamics data from a preclinical Trial in Asthma presented at the 121st International Conference of the American Thoracic Society (ATS-2025)
  • 28 Feb 2025 Pharmacokinetics and pharmacodynamics data from a preclinical trial in Asthma presented at the 2025 Annual Meeting of the American Academy of Allergy, Asthma and Immunology (AAAAI-2025)

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