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DB 1317

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Drug Profile

DB 1317

Alternative Names: DB-1317

Latest Information Update: 30 Oct 2025

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At a glance

  • Originator Duality Biologics
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunotoxins
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 23 Sep 2025 Phase-I clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA, Australia (IV) (NCT07141706)
  • 26 Aug 2025 DualityBio plans a phase I trial for Solid tumors (Inoperable/Unresectable; Late-stage disease; Metastatic disease; ​Second-line therapy or greater) in the US and Australia (IV) in September 2025 (NCT07141706)
  • 02 Sep 2024 DB 1317 is available for licensing as of 02 Sep 2024. https://www.dualitybiologics.com/partnership.html

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