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TMER1 i

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Drug Profile

TMER1 i

Alternative Names: CT-3001; TMER1-i

Latest Information Update: 07 Feb 2025

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At a glance

  • Originator Crossignal Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action GPR35 protein antagonists; Hippo signaling pathway modulators; Indoleamine-pyrrole 2,3-dioxygenase inhibitors; YAP-signaling protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 20 Sep 2024 Phase-I/II clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater, Monotherapy)(PO) (Crossignal Therapeutics pipeline, September 2024) (NCT06598007)
  • 02 Sep 2024 Phase-I/II clinical trials in Solid tumours (Combination therapy) (PO), prior to September 2024 (Crossignal Therapeutics pipeline, September 2024)
  • 05 Apr 2024 Preclinical trials in Solid tumours in USA (PO), prior to April 2024

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