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YKST 02

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Drug Profile

YKST 02

Alternative Names: anti-CD3×BCMA bispecific antibody; BCMA-CD3 bispecific antibody; YKST-02

Latest Information Update: 14 Apr 2026

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At a glance

  • Originator Excyte Biopharma
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Multiple myeloma
  • Preclinical IgA nephropathy

Most Recent Events

  • 06 Apr 2026 Huazhong University of Science and Technology plans a phase I trial for System lupus erythematosus (Monotherapy, Combination therapy, Treatment-experienced) in China (IV) in May 2026 (NCT07512947)
  • 27 Mar 2026 Union Hospital plans a phase 0 trial for IgA nephropathy in China (IV, Infusion) (NCT07498673)
  • 03 Sep 2024 Preclinical trials in IgA nephropathy in China (IV) before September 2024 (Excyte Biopharma pipeline, September 2024)

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