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GEN 1057

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Drug Profile

GEN 1057

Alternative Names: GEN-1057

Latest Information Update: 05 Jun 2026

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At a glance

  • Originator Genmab
  • Class Antibodies; Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Fibroblast activation protein alpha agonists; T lymphocyte stimulants; TRAIL receptor 1 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 20 May 2026 Discontinued - Phase-I for Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in Japan (IV)
  • 20 May 2026 Discontinued - Phase-I for Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in Spain (IV)
  • 20 May 2026 Discontinued - Phase-I for Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV)

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