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XmAb 942

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Drug Profile

XmAb 942

Alternative Names: XmAb-942

Latest Information Update: 12 Aug 2026

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At a glance

  • Originator Xencor
  • Class Anti-inflammatories; Monoclonal antibodies
  • Mechanism of Action Tumour necrosis factor ligand superfamily member 15 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Ulcerative colitis
  • Phase I/II Inflammatory bowel diseases

Most Recent Events

  • 04 May 2026 Adverse event, pharmacodynamics and pharmacokinetics data from a phase I trial in Ulcerative colitis released by Xencor
  • 02 May 2026 Pharmacokinetics, pharmacodynamics and adverse events data from a phase I/II trial in Inflammatory bowel disease presented at the Digestive Disease Week 2026 (DDW-2026)
  • 06 Aug 2025 Phase-II clinical trials in Ulcerative colitis (Treatment-experienced) in Unknown location (SC)

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