Drug Profile

CRMA 1001

Alternative Names: CRMA-1001

Latest Information Update: 17 Nov 2025

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At a glance

Originator Chroma Medicine
Developer nChroma Bio
Class Antivirals; Gene therapies
Mechanism of Action Gene silencing

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Preclinical Hepatitis B; Hepatitis D

Most Recent Events

10 Nov 2025 Chroma Bio files an clinical trial application for Hepatitis B
10 Nov 2025 Pharmacodynamics and adverse events data from a preclinical studies in Heaptitis B released by Chroma Medicine
07 Nov 2025 Chroma Bio plans a first-in-human phase I trial for Hepatitis B in early 2026

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