Drug Profile

CRMA 1001

Alternative Names: CRMA-1001

Latest Information Update: 13 Oct 2025

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At a glance

Originator Chroma Medicine
Developer nChroma Bio
Class Antivirals; Gene therapies
Mechanism of Action Gene silencing

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Preclinical Hepatitis B; Hepatitis D

Most Recent Events

30 Sep 2025 nChroma Bio plans a phase I/II trial for Hepatitis B (Treatment experienced) (IV, infusion) (NCT07200193)
12 Dec 2024 Preclinical trials in Hepatitis D in USA (IV)
12 Dec 2024 Chroma medicine plans to submit a clinical trial application in 2025

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