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Pumecitinib gel - Prime Gene Therapeutics

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Drug Profile

Pumecitinib gel - Prime Gene Therapeutics

Alternative Names: PG-011

Latest Information Update: 17 Sep 2025

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At a glance

  • Originator Prime Gene Therapeutics
  • Class Acetonitriles; Amines; Anti-inflammatories; Antiallergics; Azetidines; Pyrazoles; Pyrimidines; Pyrroles; Skin disorder therapies; Small molecules; Sulfones
  • Mechanism of Action Janus kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II/III Atopic dermatitis; Seasonal allergic rhinitis
  • Phase II Prurigo nodularis
  • Phase I Dermatitis; Epidermolysis bullosa; Radiodermatitis; Vitiligo

Most Recent Events

  • 17 Sep 2025 Chemical structure information added.
  • 28 Aug 2025 Prime Gene Therapeutics plans a phase III trial for Seasonal allergic rhinitis in China (Intranasal) (NCT07146126)
  • 01 Mar 2025 Phase-II/III clinical trials in Seasonal allergic rhinitis in China (Intranasal) (NCT06837233) (Prime Gene Therapeutics pipeline, March 2025)

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