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AI 081

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Drug Profile

AI 081

Alternative Names: AI-081

Latest Information Update: 30 Jul 2025

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At a glance

  • Originator AcroImmune
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Programmed cell death 1 receptor antagonists; T lymphocyte stimulants; Vascular endothelial growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 22 Jul 2025 National Medical Products Administration (NMPA) China clears the phase II portion of the phase I/II BIPAVE-001 trial in Solid tumours
  • 22 Jul 2025 Adverse events, pharmacokinetics and efficacy data from a phase I/II trial in Solid tumours released by OncoC4
  • 22 Jul 2025 Pharmacodynamics data from a preclinical studies in Solid tumours released by AcroImmune

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