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SEP 786

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Drug Profile

SEP 786

Alternative Names: SEP-786

Latest Information Update: 03 Mar 2025

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At a glance

  • Originator Septerna
  • Class Small molecules
  • Mechanism of Action Parathyroid hormone receptor type 1 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Hypoparathyroidism

Most Recent Events

  • 18 Feb 2025 Adverse events data from preclinical studies in Hypoparathyroidism released by Septerna
  • 18 Feb 2025 Efficacy and adverse events data from a phase I trial in Hypoparathyroidism (In volunteers) released by Septerna
  • 18 Feb 2025 Septerna terminates a phase I trial in Hypoparathyroidism (In volunteers) (PO) due to unanticipated severe (Grade 3) adverse events

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