Drug Profile

ONC 783

Alternative Names: ONC-783

Latest Information Update: 19 Feb 2026

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At a glance

Originator OncoC4
Class Antineoplastics; Bispecific antibodies; Immunotherapies; Monoclonal antibodies; Recombinant fusion proteins
Mechanism of Action Cytotoxic T lymphocyte stimulants; Immunologic cytotoxicity

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

13 Feb 2026 OncoC4 plans a phase I trial for Solid tumours (Late-stage disease, Metastatic disease) in USA (SC,Injection) (NCT07408258)
25 Sep 2024 Preclinical trials in Solid tumours in USA (SC) prior to September 2024 (OncoC4 pipeline, February 2026)
25 Sep 2024 Preclinical trials in Haematological malignancies in USA (Parenteral), prior to September 2024

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