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GRC 65327

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Drug Profile

GRC 65327

Alternative Names: GRC-65327

Latest Information Update: 04 Jul 2025

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At a glance

  • Originator Ichnos Glenmark Innovation
  • Developer Ichnos Glenmark Innovation; National Cancer Institute (USA)
  • Class Antineoplastics; Small molecules
  • Mechanism of Action CBLB protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Triple negative breast cancer

Most Recent Events

  • 25 Apr 2025 Pharmacodynamics, adverse events and pharmacokinectics data from preclinical studies in Solid tumours presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025) .
  • 30 Sep 2024 Ichnos Glenmark Innovation entered into a Cooperative Research and Development Agreement (CRADA) with the National Cancer Institute on evaluating GRC 65327
  • 30 Sep 2024 Preclinical trials in Triple-negative-breast-cancer in USA (PO)

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