Drug Profile

NNC 0537 1482

Alternative Names: NN-6537; NNC 0537-1482

Latest Information Update: 08 Sep 2026

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At a glance

Originator Novo A/S
Class Cyclic peptides; Heart failure therapies; Natriuretic peptides; Recombinant proteins
Mechanism of Action C-type natriuretic peptide modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

10 Aug 2026 Novo Nordisk plans a phase I pharmacokinetic trial for Heart failure (In volunteers, In adults, In the elderly) in Germany, in September 2026 (CTIS2026-525271-57-00)
23 Oct 2025 Phase-I clinical trials in Heart failure in United Kingdom (SC) (NCT07218627)
20 Oct 2025 Novo Nordisk plans a phase I trial for Heart failure in United Kingdom (SC) in October 2025 (NCT07218627)

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