Drug Profile

NNC 0537 1482

Alternative Names: NN-6537; NNC 0537-1482

Latest Information Update: 29 Dec 2025

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At a glance

Originator Novo A/S
Class Cyclic peptides; Heart failure therapies; Natriuretic peptides; Recombinant proteins
Mechanism of Action C-type natriuretic peptide modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

23 Oct 2025 Phase-I clinical trials in Heart failure in United Kingdom (SC) (NCT07218627)
20 Oct 2025 Novo Nordisk plans a phase I trial for Heart failure in United Kingdom (SC) in October 2025 (NCT07218627)
04 May 2025 Novo Nordisk completes a phase-I clinical trials in Heart failure (In volunteers) in Netherlands (SC) (NCT06625307)

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