Drug Profile

ATX 559

Alternative Names: ATX-559

Latest Information Update: 30 Dec 2025

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At a glance

Originator Accent Therapeutics
Class Antineoplastics; Small molecules
Mechanism of Action DHX9 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I/II Solid tumours

Most Recent Events

22 Oct 2025 Adverse events and pharmacodynamics data from preclinical studies in Solid tumours presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2025 (AACR-NCI-EORTC-2025)
22 Oct 2025 Pharmacodynamic data from preclinical studies in Solid tumours released by Accent Therapeutics
28 Apr 2025 Pharmacodynamic and adverse events data from preclinical studies in Solid tumours released by Accent Therapeutics

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