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SL 325

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Drug Profile

SL 325

Alternative Names: SL-325

Latest Information Update: 12 Jun 2026

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At a glance

  • Originator Shattuck Labs
  • Class Anti-inflammatories; Bispecific antibodies; Monoclonal antibodies
  • Mechanism of Action Tumour necrosis factor ligand superfamily member 15 inhibitors; Tumour necrosis factor member 25 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Inflammatory bowel diseases

Most Recent Events

  • 08 Jun 2026 Adverse events, pharmacokinetics, pharmacodynamics and immunogenicity data from a phase-I trial in Inflammatory bowel diseases released by Shattuck Labs
  • 05 Mar 2026 Shattuck plans the phase IIb RECEPTIVE-CD1 trial for Crohn’s disease in the US, Canada, and Europe (IV) in the third quarter of 2026
  • 05 Sep 2025 Phase-I clinical trials in Inflammatory bowel diseases (In volunteers) in USA (Parenteral) (NCT07158437)

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