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GB 3226

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Drug Profile

GB 3226

Alternative Names: BRM-1420; GB-3226

Latest Information Update: 20 Nov 2025

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At a glance

  • Originator Rockefeller University
  • Developer Galecto Inc
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Fms-like tyrosine kinase 3 inhibitors; Transcription factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Acute myeloid leukaemia

Most Recent Events

  • 10 Nov 2025 Galecto receives constructive feedback from the US FDA in response to its pre-Investigational New Drug (pre-IND) submission
  • 03 Nov 2025 Pharmacokinetics and adverse events data from preclinical studies in Acute myeloid leukaemia (AML) released by Galecto
  • 24 Jul 2025 Galecto plans a phase I/II trial for Acute myeloid leukaemia (Second-line therapy or greater) (PO), in June 2026 (NCT07084584)

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