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GB 3226

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Drug Profile

GB 3226

Alternative Names: BRM-1420; GB-3226

Latest Information Update: 17 Jul 2026

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At a glance

  • Originator Rockefeller University
  • Developer Damora Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Fms-like tyrosine kinase 3 inhibitors; Transcription factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Acute myeloid leukaemia

Most Recent Events

  • 06 Jul 2026 Galecto Biotech withdrew phase I study in Acute Myeloid Leukemia (Second-line therapy or greater, Monotherapy, Combination therapy) before enrollment due to business priority changes (NCT07084584)
  • 10 Mar 2026 Galecto Inc is now called Damora Therapeutics
  • 06 Dec 2025 Pharmacodynamics, adverse events and pharmacokinetics data from a Preclinical trials in Acute myeloid leukaemia presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-2025)

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