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ADCE D01

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Drug Profile

ADCE D01

Alternative Names: ADCE-D01

Latest Information Update: 13 Oct 2025

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At a glance

  • Originator ADCendo
  • Class Antibodies; Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Soft tissue sarcoma

Most Recent Events

  • 09 Oct 2025 ADCE D01 receives Fast Track designation for Soft tissue sarcoma [Parenteral] (Inoperable/Unresectable, Metastatic disease, Monotherapy, Second-line therapy or greater) in USA
  • 05 Jun 2025 Phase-I/II clinical trials in Soft tissue sarcoma (Inoperable/Unresectable, Metastatic disease, Second-line therapy or greater, Monotherapy) in Belgium (Parenteral) (NCT06797999)
  • 05 Jun 2025 Phase-I/II clinical trials in Soft tissue sarcoma (Inoperable/Unresectable, Metastatic disease, Second-line therapy or greater, Monotherapy) in USA (Parenteral) (NCT06797999)

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