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KAI 4729

Drug Profile

KAI 4729

Alternative Names: HRS-4729; KAI-4729

Latest Information Update: 11 Sep 2026

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At a glance

  • Originator Jiangsu Hengrui Medicine Co.
  • Developer Jiangsu Hengrui Medicine Co.; Kailera Therapeutics
  • Class Antihyperglycaemics; Obesity therapies; Peptides
  • Mechanism of Action Gastric inhibitory polypeptide receptor agonists; Glucagon receptor agonists; Glucagon-like peptide-1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Obesity
  • Preclinical Type 2 diabetes mellitus

Most Recent Events

  • 08 Sep 2026 Fujian Shengdi Pharmaceutical plans a phase I trial for Obesity (In volunteers) in China (SC, Injection) in September 2026 (NCT07807059)
  • 22 Jun 2026 Fujian Shengdi Pharmaceutical plans a phase II trial for Metabolic Dysfunction-Associated Steatohepatitis in China in July 2026 (Parenteral, Injection) (NCT07660848)
  • 27 May 2026 Efficacy, pharmacokinetics and adverse events data from a phase I trial in Obesity released by Jiangsu Hengrui Medicine

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