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KAI 4729

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Drug Profile

KAI 4729

Alternative Names: HRS-4729; KAI-4729

Latest Information Update: 06 Feb 2025

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At a glance

  • Originator Jiangsu Hengrui Medicine Co.
  • Developer Jiangsu Hengrui Medicine Co.; Kailera Therapeutics
  • Class Antihyperglycaemics; Obesity therapies; Peptides
  • Mechanism of Action Gastric inhibitory polypeptide receptor agonists; Glucagon receptor agonists; Glucagon-like peptide-1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Obesity
  • Preclinical Type 2 diabetes mellitus

Most Recent Events

  • 16 Jan 2025 Phase-I clinical trials in Obesity (In volunteers) in China (SC) (NCT06762600)
  • 07 Jan 2025 Fujian Shengdi Pharmaceutical plans a phase I trial for Obesity (In volunteers) in China (SC) in January 2025 (NCT06762600)
  • 01 Oct 2024 Preclinical trials in Diabetes mellitus in USA (unspecified route) piror to October 2024 (Kailera Therapeutics pipeline; October 2024)

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