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AVA 6103

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Drug Profile

AVA 6103

Alternative Names: AVA-6103; FAP-Exatecan; FAP-Exd

Latest Information Update: 06 Apr 2026

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At a glance

  • Originator Avacta
  • Class Alkaloids; Antineoplastics; Camptothecins; Peptide drug conjugates
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 16 Mar 2026 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Inoperable/Unresectable) in USA (IV) (NCT07454642)
  • 24 Feb 2026 Pharmacokinetics data from a preclinical trial in Cancer released by Avacta
  • 21 Jan 2026 The US FDA approves IND application for AVA 6103 in Cancer

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