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HDM 1005

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Drug Profile

HDM 1005

Alternative Names: HDM-1005

Latest Information Update: 28 Oct 2025

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At a glance

  • Originator Hangzhou Zhongmei Huadong Pharmaceutical
  • Class Antihyperglycaemics; Obesity therapies; Peptides
  • Mechanism of Action Gastric inhibitory polypeptide receptor agonists; Glucagon-like peptide-1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Obesity; Type 2 diabetes mellitus

Most Recent Events

  • 20 Jun 2025 Adverse events, pharmacokinetics and pharmacodynamics data from a phase Ia and phase Ib trial in Obesity presented at the 85th Annual Scientific Sessions of the American Diabetes Association (ADA-2025)
  • 30 Apr 2025 Phase-II clinical trials in Type 2 diabetes mellitus in China (SC) (NCT07109700)
  • 14 Feb 2025 Hangzhou Zhongmei Huadong Pharmaceutical completes a phase Ib trial in Obesity (In volunteers) in China (SC) (NCT06637020) (CTR20241919)

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