Drug Profile

Domatinostat/Sirolimus - Healx

Alternative Names: HLX-4310; Sirolimus/Domatinostat - Healx; VUJ-100

Latest Information Update: 30 Sep 2025

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At a glance

Originator Vuja De Sciences
Developer Healx
Class Anti-infectives; Anti-inflammatories; Antiepileptic drugs; Antifungals; Antineoplastics; Benzamides; Cardiovascular therapies; Eye disorder therapies; Lactones; Macrolides; Nootropics; Polyenes; Pyrazoles; Pyridines; Pyrroles; Skin disorder therapies; Small molecules; Sulfones
Mechanism of Action Histone deacetylase inhibitors; MTOR protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

23 Sep 2025 Vuja De Sciences has been acquired and merged into Healx
23 Sep 2025 Healx plans the clinical trials of Domatinostat/Sirolimus in 2025
24 Oct 2024 Chemical structure information added

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