Drug Profile

ANS 03

Alternative Names: ANS-03

Latest Information Update: 26 Jun 2025

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At a glance

Originator Avistone Pharmaceuticals
Class Antineoplastics; Small molecules
Mechanism of Action ROS1 protein inhibitors; TrkA receptor antagonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Solid tumours

Most Recent Events

25 Apr 2025 Pharmacodynamics data from a preclinical trial in Solid tumours presented at the 116^th Annual Meeting of the American Association for Cancer Research (AACR-2025)
06 Mar 2025 Phase-I clinical trials in Solid tumours (Metastatic disease, Late-stage disease, Monotherapy) in China (PO) (NCT06716138)
04 Dec 2024 Avistone Pharmaceuticals plans a phase I trial for Solid tumours (Late-stage disease, Metastatic disease) in China and USA (NCT06716138)

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