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AP 402

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Drug Profile

AP 402

Alternative Names: AP-402

Latest Information Update: 08 May 2025

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At a glance

  • Originator AP Biosciences
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action Cytotoxic T lymphocyte stimulants; Immunologic cytotoxicity
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 29 Apr 2025 Adverse events, pharmacodynamics and pharmacokinetics data from a preclinical trial in Solid tumours released by AP Biosciences
  • 22 Apr 2025 Phase-I/II clinical trials in Solid tumours (Late-stage disease, Inoperable/Unresectable, Metastatic disease) in Australia (IV) (NCT06669975)
  • 28 Feb 2025 Therapeutic Goods Administration (TGA) Australia approves IND application for AP 402 in Solid tumours

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