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REGN 7945

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Drug Profile

REGN 7945

Alternative Names: CD38xCD28 antibody - Regeneron Pharmaceuticals; REGN-7945

Latest Information Update: 20 Feb 2025

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At a glance

  • Originator Regeneron Pharmaceuticals
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD28 antigen inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Multiple myeloma

Most Recent Events

  • 11 Dec 2024 Phase-I/II clinical trials in Multiple myeloma (Combination therapy, Second-line therapy or greater) in Australia (Parenteral) (NCT06669247)
  • 07 Dec 2024 Pharmacodynamics data from preclinical trials in Multiple myeloma presented at the 66th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2024)
  • 01 Nov 2024 Regeneron Pharmaceuticals plans a phase I/II trial for Multiple myeloma (Second line therapy or greater, Combination therapy) in December 2024 (parenteral) (NCT06669247)

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