Drug Profile

RNK 08954

Alternative Names: RNK-08954

Latest Information Update: 20 Jan 2026

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At a glance

Originator Ranok Therapeutics
Class Antineoplastics; Small molecules
Mechanism of Action KRAS protein degraders

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Adenocarcinoma
Phase I/II Solid tumours

Most Recent Events

31 Dec 2025 Ranok Therapeutics plans a phase I mass balance study trial in Healthy volunteers in China in December 2025 (PO) (NCT07334262)
14 Oct 2025 Phase-II clinical trials in Adenocarcinoma (Metastatic disease) in China (PO) (NCT07303465)
04 Apr 2025 Phase-I/II clinical trials in Solid tumours (Metastatic disease, Late-stage disease, Second-line therapy or greater) in China (PO) (NCT06667544) (NCT06667544)

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