Drug Profile

RNK 08954

Alternative Names: RNK-08954

Latest Information Update: 18 Apr 2025

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At a glance

Originator Ranok Therapeutics
Class Antineoplastics; Small molecules
Mechanism of Action KRAS protein degraders

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I/II Solid tumours

Most Recent Events

04 Apr 2025 Phase-I/II clinical trials in Solid tumours (Metastatic disease, Late-stage disease, Second-line therapy or greater) in China (PO) (NCT06667544) (NCT06667544)
31 Oct 2024 Ranok Therapeutics plans the phase-I/II TRIAD1 trial for Solid tumours (Late-stage disease; Metastatic disease; Second-line therapy or greater) in USA (PO), (NCT06667544)
31 Oct 2024 Preclinical trials in Solid tumours in USA (PO) prior to October 2024

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