Drug Profile

JADE 001

Alternative Names: JADE-001; PR-030

Latest Information Update: 10 Sep 2025

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At a glance

Originator Paragon Therapeutics
Developer Jade Biosciences
Class Monoclonal antibodies
Mechanism of Action Tumour necrosis factor ligand superfamily member 13 inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I IgA nephropathy

Most Recent Events

10 Sep 2025 Phase-I clinical trials in IgA nephropathy (Parenteral), prior to September 2025 (Jade Biosciences pipeline, September 2025)
31 Oct 2024 Jade Biosciences plans a first-in-human clinical trial for IgA nephropathy (Parenteral) in second half of 2025
31 Oct 2024 Paragon Therapeutics files provisional patent applications covering the subject matter of JADE 001 before October 2024

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